Spectroscopic constrains on variation of fundamental constants in astrophysics.

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I will discuss present limits on the variation of the fine structure constant and the electron to proton mass ratio from the astrophysical data on the spectra from the interstellar gas medium. The emphasis will be made on the infrared and microwave spectra. Such spectra may be 2 - 3 orders of magnitude more sensitive to the variation of constants than optical spectra.